Page last updated: 2024-09-04

ezetimibe and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ezetimibe has been researched along with (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid in 16 studies

Compound Research Comparison

Studies
(ezetimibe)
Trials
(ezetimibe)
Recent Studies (post-2010)
(ezetimibe)
Studies
((3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid)
Trials
((3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid)
Recent Studies (post-2010) ((3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid)
2,4845631,4651,459368396

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (56.25)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Császár, A; Márk, L1
Battisti, WP; Brady, WE; Denke, MA; McBride, PE; Palmisano, J; Pearson, TA1
Cutler, DL; Kosoglou, T; Maxwell, S; Reyderman, L; Statkevich, P1
Heemann, U; Kohnle, M; Kribben, A; Philipp, T; Pietruck, F; Witzke, O1
Alonso-Villaverde, C; Aragonés, G; Coll, B; Masana, L; Parra, S1
Ballantyne, CM; Gimpelewicz, CR; Seper, C; Sirnes, PA; Stein, EA; Sussekov, A; Windler, E; Yigit, Z1
Alvarez-Sala, LA; Cachofeiro, V; Gambus, G; Lahera, V; Masana, L; Moreno, MA; Pinilla, B; Pintó, X; Plana, N; Suarez, C; Trias, F1
Doggrell, SA1
Abletshauser, C; Geisen, U; Hoffmann, MM; Odünc, N; Pütz, G; Schäfer, G; Schewe, T; Siegel, E; Winkler, K1
Visseren, FL; Westerink, J1
de Campo, A; März, W; Scharnagl, H; Schmölzer, I; Sourij, H; Stojakovic, T; Wascher, TC1
Aoki, C; Hattori, Y; Iijima, T; Jojima, T; Kasai, K; Kase, H; Kawagoe, Y; Nakano, A; Ohta, S; Tanaka, S; Tomizawa, A1
Parhofer, KG1
Bokuda, K; Ichihara, A; Itoh, H; Kinouchi, K; Morimoto, S1
Asakura, Y; Habara, M; Ito, T; Kimura, M; Kinoshita, Y; Ko, E; Kurita, T; Matsubara, T; Nasu, K; Suzuki, T; Teramoto, T; Terashima, M; Tsuchikane, E; Yokota, D1
Macchi, C; Magni, P; Morlotti, B; Ruscica, M; Sirtori, CR1

Reviews

3 review(s) available for ezetimibe and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
[Antilipemic agents in combined therapy].
    Orvosi hetilap, 2002, Aug-25, Volume: 143, Issue:34

    Topics: Anticholesteremic Agents; Apolipoproteins; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Fenofibrate; Fluvastatin; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipids; Pravastatin; Simvastatin; Triglycerides; Vitamin B 12; Vitamin B 6

2002
Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:2

    Topics: Amlodipine; Anticholesteremic Agents; Atorvastatin; Azetidines; Cardiovascular Diseases; Clinical Trials as Topic; Clofibric Acid; Ezetimibe; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Indoles; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2006
Risk identification and possible countermeasures for muscle adverse effects during statin therapy.
    European journal of internal medicine, 2015, Volume: 26, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Colesevelam Hydrochloride; Creatine Kinase; Drug Interactions; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Muscular Diseases; Myalgia; Rhabdomyolysis; Risk Assessment; Risk Factors; Rosuvastatin Calcium; Sex Factors; Vitamin D Deficiency

2015

Trials

11 trial(s) available for ezetimibe and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:5

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Nephelometry and Turbidimetry; Practice Guidelines as Topic; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin

2005
The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe.
    Current medical research and opinion, 2005, Volume: 21, Issue:8

    Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Male; Middle Aged

2005
Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2006, Volume: 6, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cyclosporine; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Kidney Transplantation; Liver; Male; Middle Aged; Muscle, Skeletal; Pravastatin; Simvastatin; Tacrolimus

2006
Ezetimibe effectively decreases LDL-cholesterol in HIV-infected patients.
    AIDS (London, England), 2006, Aug-01, Volume: 20, Issue:12

    Topics: Adult; Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; Azetidines; Cholesterol; Cholesterol, LDL; Endothelium; Ezetimibe; Fatty Acids, Monounsaturated; Fluvastatin; HIV-Associated Lipodystrophy Syndrome; Humans; Indoles; Treatment Outcome

2006
Efficacy and tolerability of fluvastatin XL 80 mg alone, ezetimibe alone, and the combination of fluvastatin XL 80 mg with ezetimibe in patients with a history of muscle-related side effects with other statins.
    The American journal of cardiology, 2008, Feb-15, Volume: 101, Issue:4

    Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipoproteins; Male; Middle Aged; Muscular Diseases; Treatment Outcome; Triglycerides

2008
Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-labe
    Clinical therapeutics, 2008, Volume: 30, Issue:1

    Topics: Anticholesteremic Agents; Apolipoproteins B; Azetidines; Biomarkers; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Delayed-Action Preparations; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Interleukin-1beta; Male; Middle Aged; Triglycerides

2008
Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles.
    European journal of clinical investigation, 2009, Volume: 39, Issue:6

    Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Humans; Indoles; Male; Metabolic Syndrome; Middle Aged; Simvastatin; Treatment Outcome

2009
Differential effects of fluvastatin alone or in combination with ezetimibe on lipoprotein subfractions in patients at high risk of coronary events.
    European journal of clinical investigation, 2010, Volume: 40, Issue:3

    Topics: Aged; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Biomarkers; Cholesterol; Coronary Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Indoles; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Prospective Studies

2010
Comparative study between high-dose fluvastatin and low-dose fluvastatin and ezetimibe with regard to the effect on endothelial function in diabetic patients.
    Endocrine journal, 2011, Volume: 58, Issue:3

    Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Indoles; Male; Middle Aged; Treatment Outcome; Triglycerides; Vasodilation

2011
Effects of adding ezetimibe to fluvastatin on kidney function in patients with hypercholesterolemia: a randomized control trial.
    Journal of atherosclerosis and thrombosis, 2013, Volume: 20, Issue:3

    Topics: Adult; Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Kidney Function Tests; Male; Middle Aged

2013
Impact on optical coherence tomographic coronary findings of fluvastatin alone versus fluvastatin + ezetimibe.
    The American journal of cardiology, 2014, Feb-15, Volume: 113, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Vessels; Disease Progression; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Humans; Indoles; Male; Middle Aged; Plaque, Atherosclerotic; Prospective Studies; Tomography, Optical Coherence

2014

Other Studies

2 other study(ies) available for ezetimibe and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles.
    European journal of clinical investigation, 2010, Volume: 40, Issue:1

    Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Fenofibrate; Fluvastatin; Humans; Hypolipidemic Agents; Indoles; Metabolic Syndrome; Simvastatin

2010
[After bypass surgery nearly all lipids are in the normal range. However, Lp(a) is too high, what can be done?].
    MMW Fortschritte der Medizin, 2011, May-26, Volume: 153, Issue:21

    Topics: Azetidines; Cholesterol; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Lipoprotein(a); Male; Postoperative Complications; Prognosis; Reference Values; Risk Factors; Secondary Prevention; Treatment Outcome

2011